Inside a Cell

1 Cells and treatment

Cell line Drug …or look up any drug or structure

Concentration (µM) How long the drug is present

2 Design your own drug

Say what your drug does and watch the cell. Nothing about it is measured, so the result is your hypothesis played out by the engine, and it is labelled that way.

Name What it does

Which molecule How tightly it binds (Kd) How much, when fully bound

3 Try one of these

4 Which cell to watch

Simulate first.

Each simulated cell starts at a different point in its cycle and carries its own small differences, which is why the same drug does not do the same thing to all of them.

5 What this does not show

Each circle is one molecular species as the engine tracks it — a single normalised level, not individual molecules. The engine follows about twenty of them; a real cell has thousands of proteins and its own metabolism, none of which appear here. The arrows are the interactions the engine models, not every one that exists.

Watch what happens inside one cell

Pick a scenario on the left. Every circle lights up with the real level of that molecule as the engine computes it, minute by minute.

0.0 h

This cell, right now

—

Nothing simulated yet.

What happened

Events appear here as they happen.